Tadalafil,CAS:171596-29-5

Chemical Name:(6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyridol[3,4-b]indole-1,4-dione
MF:C22H19N3O4
Purpose:Treatment of male erectile dysfunction

Classification :

PRODUCT DETAILS

Specifications

Product Name

(6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2'-1,6]pyridol[3,4-b]indole-1,4-dione

CAS No.

171596-29-5

Test Standard

Enterprise standard

 

Items

Standard

Appearance

White or almost white powder

Identification

1) The infrared absorption spectrum is concordant with the reference spectrum.
2) In the chromatogram under isomer test items,the principal peak in the chromatogram obtained with the test solution should be consistent with the retention time of the main peak of the reference solution.

Solubility

Easily soluble in dimethyl sulfoxide,slightly soluble in acetonitrile and dichloromethanedifficult to dissolve in methanolalmost insoluble in water.

Optical rotation

+78.0°+84.0°

Chloride

≤0.02%

Loss on drying

0.5%

Residue on ignition

0.1%

 

Residual solvent

Methanol ≤0.3%

 

Dichloromethane ≤0.06%

 

Acetonitrile ≤0.041%

 

Ethyl acetate0.5%

Related Substances

Impurity A0.1%

 

ImpurityB0.1%

 

Impurity C0.1%

 

Unidentified single impurity0.5%

 

Total impurities1.0%

Purity

≥99.0%

Packaging

Inner packaging:two-layer LDPE bags, Outer packaging:cardboard drum,
Net weight:25.00kg/drum.

Storage Conditions

Room temperature, sealdry place

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