Crisaborole ,CAS:906673-24-3

Chemical Name:4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzonitrile
MF: C14H10BNO3
Purpose:Used for non infectious, mild to moderate atopic dermatitis, especially for patients who are intolerant to steroid drugs or require long-term treatment

Classification :

PRODUCT DETAILS

Specifications

Product Name

4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzonitrile

CAS No.

906673-24-3

Test Standard

Enterprise standard

 

Items

Standard

Appearance

White to off white powder


Identification

1)The infrared absorption spectrum is concordant with the reference spectrum.

2)HPLC: the retention time of the principal peak is similar to the reference spectrum

Solubility

Very soluble in DMF,soluble in isopropanol and propylene glycol,soluble in ethanol, acetonitrile and methylene chloride,slightly soluble in methanol,insoluble in water

Residue on ignition

0.1%

Loss on drying

0.5%

Heavy Metals

≤10ppm

Residual solvent

Methanol 0.3%

Isopropyl alcohol0.5%

Dichloromethane ≤0.06%

N-heptane0.5%

Tetrahydrofuran ≤0.072%

Ethyl acetate0.5%

Related Substance

Any other individual impurity ≤0.1%

Total impurities≤1.0%

Purity

99.0%

Assay

98.0%-102.0%

Packaging

Inner packaging:two-layer LDPE bags, Outer packaging:cardboard drum,
Net weight:25.00kg/drum.

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